Studies on Haptoglobin. I
نویسندگان
چکیده
منابع مشابه
Immunological and Biochemical Studies on Serum Haptoglobin
Antibody to purified type 1-1 human serum haptoglobin was obtained in rabbits. Using this antiserum it was demonstrated that the antigenic determinants of the haptoglobin molecule reside in both alpha- and beta-chains. No immunological difference between the normal alpha(1F)- and alpha(1S)-chains of haptoglobin could be detected. A number of healthy individuals whose haptoglobin pattern appeare...
متن کاملHaptoglobin Synthesis. I. in Vivo Studies of the Production of Haptoglobin, Fibrinogen, and Gamma-globulin by the Canine Liver.
Haptoglobin is an a2 plasma glycoprotein that forms a stable complex with hemoglobin (1-5). The complex is cleared from the plasma much more rapidly than free haptoglobin so that marked hypoor anhaptoglobinemia is a concomitant of hemolysis (6, 7). Since free hemoglobin passes readily into the urine, whereas the complex, perhaps owing to its much greater size, does not, haptoglobin may play a r...
متن کاملStudies on the serum haptoglobin level in hemoglobinemia and its influence on renal excretion of hemoglobin.
JAYLI:’ foiiiid that oti addition of a si ttI1 ai ount of hen og1ohin, rtiin shows weak peroxidase a(tivity with au optiintii around pH 4.4 in sJ)itP of the fact that no 50(11 a(1ivitv ean })e dei oiistiated in either suI)stan(e hv itS( 1f. In later investigations iii association with POlOliOVski he (lemonstrated that a complex l)et\VN9I hemoglobin (Jib) an(l a serum protein is responsible for ...
متن کاملPharmacological studies on fatigue. I.
Considerable investigation has been done as to whether or not a particular drug is effective for recovery of an animal after it has become exhausted. Experiments have included screening antifatigue effect on animals, but applications have not been generally established. Effects of drugs on psychological fatigue as seen in man can hardly be inferred from tests on animals. Even physiological effe...
متن کاملAssignment of the binding site for haptoglobin on apolipoprotein A-I.
Haptoglobin (Hpt) was previously found to bind the high density lipoprotein (HDL) apolipoprotein A-I (ApoA-I) and able to inhibit the ApoA-I-dependent activity of the enzyme lecithin:cholesterol acyltransferase (LCAT), which plays a major role in the reverse cholesterol transport. The ApoA-I structure was analyzed to detect the site bound by Hpt. ApoA-I was treated by cyanogen bromide or hydrox...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Proceedings of the Japan Academy
سال: 1970
ISSN: 0021-4280
DOI: 10.2183/pjab1945.46.820